Immunoglobulin
G4-related disease is a systemic disease that can virtually involve any organs including the biliary tract and
liver. In biliary tract involvement of IgG4-RD is known as IgG4-sclerosing
cholangitis (IgG4-SC) and may or may not present with an inflammatory pseudo
tumor. Acute hepatitis and acute liver failure are severe medical conditions
which require early clinical intervention. Histopathology
findings on a liver biopsy
or a liver explant can help to identify the underlying etiology or provide an
important direction for further clinical, laboratory and radio graphical
investigation. Cryptogenic cirrhosis (CC) is defined as the cirrhosis of
unknown etiology despite extensive clinical, laboratory and pathologic work-up,
and constitutes 5-10% approx all
cirrhosis cases. The global digital market of pathology size is expected to reach USD 1.67 billion by
2026, it is anticipated to expand at a CAGR of 11.7% during the forecast
period.
